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What is Fosamax?

Fosamax is an anti-osteoporosis drug with a generic name of Alendronate Sodium. It is available in tablet and oral solution formulas. It works by preventing the degeneration of bone-forming cells. It is mainly used to treat osteoporosis induced by menopause as well as long-term corticosteroid use.

PROS:

• Fosamax prevents bone loss thereby making bones stronger.
• Fosamax is to be taken only once a week.
• Fosamax is used to prevent fractures associated with osteoporosis.

CONS:

• Fosamax is to be administered orally with an empty stomach with plain water.
• Fosamax should be taken in upright and must not lie down nor eat and drink for at least 30 minutes.

BOTTOM LINE:

• Can be taken with supplements such as Calcium, Magnesium and Vitamin D to further strengthen the bones

FULL REVIEW: FOSAMAX (Alendronate Sodium) 5 mg 8 tablets

I’m a grandmother to one kid and my own 4 children are all grown up. I’m now in my early 60s and is well on my way of my menopause. Last year, after my bi-annual comprehensive medical exam with bone density scan, my doctor informed me that I’m a candidate for osteoporosis. It shocked me because I have been a milk drinker for years and I have never felt that I have such a condition. However, my offshore pharmacies physician reassured me that my problem is related to my menopause since my estrogen (female hormone) is continuously decreasing. And so, my doctor gave me a prescription to take 5 mg of Fosamax (Alendronate sodium) to prevent further damage to my bones while I’m going through my menopause.

WHAT IS OSTEOPOROSIS?

According to my offshore pharmacies doctor, osteoporosis is the slow deterioration of the bones due to the decreased formation of bone cells. In effect, bones become brittle and porous, making it easy to break. So, those women with advanced osteoporosis have a very high risk for sustaining bone fractures. And with bone fractures, more serious complications could set in.

HOW IS OSTEOPOROSIS TREATED? CAN IT BE PREVENTED?

Yes, osteoporosis can be prevented and it can be treated. In fact, it is a reversible condition. A drug called Fosamax is specially created to treat osteoporosis as well as prevent it. What Fosamax does is that it activates new bone cell growth and prevents fast degradation of those that are already made. This drug could actually make your bones really strong and healthy.

For my treatment plan, my doctor advised me to take Fosamax only once a week. I have to create an alarm on my mobile phone’s calendar to remind me to take my medication. My doctor informed me also to take it upon waking up in the morning and that I should not be lying down within 30 minutes after I take it. It’s because Fosamax has been associated with some esophageal problems in the past and it is best that for proper absorption, I should be standing up or sitting upright when I take my Fosamax pill.

WOULD I RECOMMEND FOSAMAX TO OTHER WOMEN WITH OSTEOPOROSIS?

Yes, I’d recommend that you take Fosamax but you have to first consult your physician before taking it. It pays well to be more informed.

Fosamax (Alendronate Sodium) treats osteoporosis induced by corticosteroids and menopause. It belongs to a class of drugs known as bisphosphates that prevents breakdown of bone cells. Fosamax is relatively safe and easy to use after a thorough discussion with your physician on the benefits and risks of using this drug.

Most women in their postmenopausal period become increasingly at risk for developing fractures secondary to osteoporosis. Osteoporosis is due to the decreasing production of estrogen, a female reproductive hormone. With this condition, fractures can easily be acquired because bones tend to be more brittle when they lose their density. With Fosamax, this problem can be alleviated as bisphosphates can help make you gain healthier and stronger bones.

Fosamax is to be administered orally as it comes in tablet and oral solution forms. The tablets are white and crystalline while the syrup has a sweet raspberry flavor. Fosamax is to be taken in once a week only and after waking up in the morning. Marking your calendars will help you remember when to take your Fosamax. It would be best to identify your most convenient day of the week to keep you reminded about it.

After waking up in the morning, take one pill of Fosamax with about 3-4 gulps of plain water (about 2 ounces) and stay upright for at least 30 minutes. You can sit upright, stand or walk within this period to allow proper absorption of the drug before eating your first meal of the day. It is best not to take any other food or supplements, such as vitamins, orange juice and coffee, within 30 minutes after Fosamax intake so as not to decrease the absorption of the drug. Fosamax does not accumulate in the body of a healthy client as it is normally excreted in the urine.

Take note that if your have the following problems, you should first consult your physician about it before taking Fosamax:

• Allergies to alendronate sodium
• Inability to sit or stand upright for at least 30 minutes
• Esophageal problems
• Have decreased plasma calcium levels

Fosamax helps keep you gain better bones and changes are not that noticeable within the first 3 months of regularly taking Fosamax once per week. Have a check-up with your physician after 3-4 months to determine the effects of Fosamax in your bones. Take note that Fosamax is not a hormone. To keep your bones healthier and stronger, one should regularly take in Fosamax and never miss it.

Read the labels or leaflets attached to your medication bottles prior to taking in this drug. Discus any problems or questions that you have in mind with your pharmacist or health care provider to have a more informed decision on Fosamax administration.

Women in their postmenopausal period are usually on the verge of undergoing osteoporosis. Although osteoporosis is not always felt, after some bone mass tests and xrays, plus if the height has become decreased and there is gradual stooping, a diagnosis will then be confirmed by the physician. With Fosamax, an anti-osteoporosis drug, the risk of acquiring bone fractures secondary to osteoporosis, will be diminished and prevented.

Fosamax is a drug made by Merck. Its generic name is alendronate sodium, a bisphosphate, which is used to treat osteoporosis due to menopause or corticosteroid-induced. It has also been known to be used for other bone problems. Fosamax is being marketed in both tablet and oral solution form and it is also available as Fosamax+D in which vitamin D has been incorporated. Available Fosamax tablets come in dosages of 5mg, 10mg, 35mg, 40mg and 70mg while the oral solution form has a dosage of 70mg/75ml.

Fosamax is easy to use. It is to be taken in once every week in the morning upon waking up with at least 2 ounces (about 60ml) of plain water. Then wait for about 30 to 45 minutes, in an upright position (either you stand, sit or walk) for the drug to settle in before taking in food so as not to decrease the bioavailability of the drug in the body. One should keep in mind not to take in coffee or orange juice with Fosamax as the absorption in the body will be decreased. Studies have shown that this decrease is about 60% which will lessen the effectivity of the drug. For corticosteroid-induced osteoporosis, calcium and vitamin D supplements could be taken in after one hour of administering Fosamax. Excess Fosamax do not usually stay in the body too long among healthy clients as it is excreted in the urine. However, if one has a major renal problem, then she should talk about it with her doctor first before taking Fosamax.

This drug is not to be taken while lying down, at bedtime or before getting up in the morning as alendronate sodium has been correlated with some esophageal problems. Keep in mind to check the label or the leaflet that comes with the drug. If there are questions regarding Fosamax, it is also best to inquire with your physician or pharmacist about it. Remember to take Fosamax once a week only. It would be best also if you mark your calendars or keep an alarm system to remind you about it.

It should be noted also that with long-term use of Fosamax, the risk of developing esophageal and jaw problems are also increased. One should discuss with their physicians the relative risks and benefits with the use of this drug. A regular comprehensive check-up with a health care provider is a must every four to six months to determine any development of side effects from taking the drug.

Have you been diagnosed with osteoporosis? Osteoporosis is a clinical condition wherein bone mass has been depleted. This condition is characterized by brittled bones that are at high risk for fractures. Doctors often diagnose this disease by the presence of small bone fractures seen in x-ray films, past diagnosis of osteoporosis, presence of kyphosis as well as decreasing height. Women who are diagnosed with osteoporosis are mostly those who are into their post-menopausal stage. This is because the female hormone, estrogen, becomes depleted when the women begin to menopause. If you have been diagnosed with osteoporosis, therefore, the best treatment will be a constant supplementation of alendronate sodium, or Fosamax.

Fosamax has been created by Merck, an established international drug company, to treat osteoporosis. This drug is a potent bisphosphate known to treat not only osteoporosis but also that of other bone conditions. It is available in both tablet and oral solution forms which can be easily purchased from drugstores with prescriptions from the physician. Fosamax+D, which is alendronate sodium with vitamin D, is also available in the market.

Fosamax for osteoporosis is a prophylactic as well as treatment strategy to aide women of 50 years old and above prevent developing risks for fractures. As women grow older, their chances of getting a fracture become high. However, osteoporosis is a preventable and a reversible condition if the woman gets enough treatment with Fosamax. This can be simultaneously be used in conjunction with calcium and vitamin D to treat corticosteroid-induced osteoporosis. It has also been known to be indicated for clients with Paget’s Disease.

Although Fosamax is highly absorbed in the body tissues and excreted in the urine, studies have shown that it’s resorption rate has been decreased significantly with the intake of high levels of calcium or magnesium aluminum (or antacids).It is therefore recommended to take other supplementation after an hour of administering Fosamax. Intake of Fosamax is ideally during the morning upon waking up with at least 6-8 ounces of water. One should wait for at least 30-45 minutes for the drug to be absorbed by the body prior to eating breakfast.

Fosamax is relatively safe to use however, in 2008, the England Journal of Medicine cited that there have been 23 reported cases of esophageal cancer that are possibly related to the use of Fosamax. This drug has also been implicated with osteonecrosis of the jaw (ONJ) which was under litigation in 2008. It was claimed that increased exposure to bisphosphates could lead to the presence of ONJ. The Food and Drug Authority (FDA) asked Fosamax manufacturers to provide a warning notes to physicians regarding its side effect of developing ONJ among their clients.

Fosamax oral solutions are available at 70mg/75 ml bottles and the tablets are available in 5mg, 10mg, 35 mg, 40 mg and 70 mg.

Fosamax is simply an anti-osteoporosis drug. Osteoporosis is a medical condition wherein the human bone’s density has become more brittle due to loss of calcium. With Fosamax, one can simply say that there is finally hope for brittle bones. A product of Merck, which has a robust list of wide variety of world-renowned drugs, Fosamax’s generic name is Alendronate sodium, which are available in tablets and oral solution.

Fosamax is a bisphosphonate drug wherein it delays bone loss while increasing the formation of new bone. This drug is highly beneficial for preventing fractures and other bone-loss related problems. Although Fosamax may be used for other purposes other than those mentioned here, it has been formulated to treat mainly steroid-induced osteoporosis and postmenopausal osteoporosis. As a bisphosphate, Fosamax inhibits resorption of osteoclast-mediated bone. The tablet form is white crystalline powder that is highly soluble in water but absolutely insoluble with chloroform, while oral solutions have a sweet raspberry flavor.

Fosamax can be taken in with or without meals. Studies show that there is no significant effects if the drug was taken an hour or more after a standard breakfast. However, it should be noted that taking coffee or orange juice together with Fosamax can greatly reduce the drug’s absorption rate.

After taking Fosamax, the drug will then be widely distributed into the soft tissues before it reaches the bones and then excreted in the urine. If Fosamax is not completely absorbed by the bones of healthy clients, it will be rapidly excreted in the urine. However, animal studies on mice with kidney failure taking in Fosamax have been found to have high levels of the drug in their blood, kidneys and bones with reduced elimination of drug from the body. Therefore, it is highly recommended that clients with severe renal failure or those whose creatinine clearance is less than 35mL/min should avoid taking Fosamax.

Osteoporosis is a condition wherein the bone mass is greatly reduced thereby there is a high risk for fracture injuries. Diagnosis of osteoporosis is confirmed by presence of low-bone mass in tests, evidence of a fracture on x-ray, history of osteoporotic fracture, presence of kyphosis, or loss of height. Although this happens to both men and women, osteoporosis is more common with women especially at the time of menopause. Many postmenopausal women over age 50 have been found to have progressive bone loss leading to osteoporosis in high percentage. From around ages 50 to 90 years, it has been reported that women are 50x at risk of suffering hip fractures while 30-50x at risk of vertebral fracture. Studies have shown that by taking daily doses of Fosamax, postmenopausal women have decreased calcium released from their body. Long-term users have been reported that the urinary release of bone resorption markers have decreased to about 50%- 70%.